SS-31 50mg

SS-31 is a mitochondria-targeted tetrapeptide (D-Arg-Dmt-Lys-Phe-NH₂) that selectively penetrates mitochondrial membranes to bind cardiolipin, stabilizing cristae architecture, optimizing electron transport chain efficiency, and preventing reactive oxygen species (ROS) leakage at the source—delivering 20-40% ATP production increases while reducing oxidative damage across aging tissues. Unlike broad antioxidants that fail to reach mitochondria, SS-31’s cationic structure ensures compartmentalized action where 90% of cellular energy and ROS generation occurs, preserving Complex I-IV function and ADP sensitivity impaired in sarcopenia and neurodegeneration.

Clinical research demonstrates restored muscle function in aging models, neuroprotection against LPS-induced cognitive decline, and reversal of mitochondrial dysfunction in heart failure and kidney disease. Benefits span enhanced exercise tolerance (12% VO2 max improvement), reduced fatigue, preserved synaptic plasticity, and systemic metabolic resilience without exercise. For individuals over 50 experiencing energy decline, mitochondrial diseases, or neurodegenerative risk, SS-31 offers direct cellular powerplant restoration—addressing aging’s core bioenergetic failure.